Prostatic Intraepithelial Neoplasia (PIN)

Prostatic intraepithelial neoplasia (PIN) is a condition in which some of the prostate’s epithelial cells look abnormal under the microscope. Epithelial cells are the cells that line the tiny sacs in the prostate and the ducts that carry fluid in the prostate. Sometimes the abnormalities are minor, but sometimes they start to look like the cellular changes characteristic of cancer cells. Whether PIN will progress to cancer and what, if anything, should be done to treat it remains unclear.

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What is prostatic intraepithelial neoplasia (PIN)?

No consensus exists about what type of medical follow-up is in order for this “precancerous” condition or whether to treat it. Marc B. Garnick, M.D., explains the condition and outlines your options.

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Can pathologists accurately and reliably diagnose PIN?

Study shows that many patients are misdiagnosed with PIN, possibly leading unnecessary prostate biopsies

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